Hemospray in Pulmonary Hemorrhage: A Novel Approach for Immediate and Sustained Hemostasis”
This article discusses two cases of successfully managed pulmonary hemorrhage using TC-325, commonly known as Hemospray. Initially approved for endoscopic hemostasis in gastrointestinal bleeding, Hemospray’s application in controlling endobronchial bleeding has been underreported.
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Hemospray
The cases underscore its effectiveness in achieving immediate and sustained hemostasis in peripheral pulmonary bleeding, particularly when conventional bronchoscopic therapies prove ineffective. The absence of adverse effects and rapid cessation of bleeding highlight Hemospray’s potential as a valuable tool in managing life-threatening hemoptysis scenarios.
Case Presentation:
The first case involves a 76-year-old lady undergoing neoadjuvant chemoimmunotherapy for breast cancer, while the second case features a 62-year-old gentleman with metastatic carcinoid cancer. In both cases, Hemospray demonstrated immediate hemostasis, providing a pragmatic solution for challenging bleeding sources not amenable to traditional interventions.
Discussion:
Hemospray, a non-contact, chemically inert hemostatic powder, has shown success in upper gastrointestinal bleeding. However, its application in endobronchial bleeding control has not been widely recognized. The cases presented highlight the potential of Hemospray in achieving rapid hemostasis in patients with peripheral sources of hemoptysis, where identifying an endobronchial source is challenging. The powder’s dual mechanism, forming a mechanical barrier and promoting local clotting, offers a safe and effective approach without the risk of systemic toxicity.
Conclusion:
While further studies are needed to validate Hemospray’s efficacy and safety in a larger cohort, these cases suggest its potential as a game-changer in comprehensive hemoptysis management. Hemospray’s ease of application and quick hemostatic effects position it as a pragmatic solution for cases with challenging bleeding sources. The article advocates considering Hemospray as a valuable addition to the bronchoscopist’s arsenal, addressing limitations associated with conventional interventions.
